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Importantly, these receptors were being located to have been activated by a variety of endogenous opioids in a focus much like that observed for activation and signaling of classical opiate receptors. In turn, these receptors were found to have scavenging exercise, binding to and reducing endogenous levels of opiates available for binding to opiate

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Importantly, these receptors ended up found to happen to be activated by an array of endogenous opioids at a focus comparable to that noticed for activation and signaling of classical opiate receptors. Consequently, these receptors have been observed to possess scavenging activity, binding to and lowering endogenous amounts of opiates obtainable fo

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